tert-butyl 2-(4-chlorophenyl)acetate - Names and Identifiers
tert-butyl 2-(4-chlorophenyl)acetate - Physico-chemical Properties
Molecular Formula | C12H15ClO2
|
Molar Mass | 226.7 |
Boling Point | 78-80°C/0.1mm |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD08687454 |
tert-butyl 2-(4-chlorophenyl)acetate - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
tert-butyl 2-(4-chlorophenyl)acetate - Introduction
4-(Chlorophenyl)acetic acid tert-butyl ester (tert-butyl 4-chlorophenylacetate) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C11H13ClO2
-Molecular weight: 214.67g/mol
-melting point: 44-47 ℃
-Boiling point: 296 ℃
-Solubility: Soluble in organic solvents such as ether and xylene, slightly soluble in water.
Use:
4-(Chlorophenyl)acetic acid tert-butyl ester can be used for esterification reaction or acylation reaction in organic synthesis reaction. When it is used as an esterifying agent, it can be used to synthesize other organic compounds, such as pharmaceutical intermediates and pesticide intermediates.
Preparation Method:
A commonly used preparation method is to react 4-chlorophenylacetic acid and tert-butanol under acidic conditions to generate 4-(Chlorophenyl)acetic acid tert-butyl ester. The reaction may be carried out under heating, and a catalyst is used to promote the progress of the reaction.
Safety Information:
4-(Chlorophenyl)acetic acid tert-butyl ester is generally safe under correct operation. However, it can be irritating to the eyes, skin and respiratory tract. Wear goggles, gloves and respiratory protection during use or handling. Avoid direct contact with skin and inhalation of dust. If exposed or inhaled, rinse immediately with water and seek medical help. At the same time, it should be stored in a cool, dry, well-ventilated place, away from fire and combustibles.
Last Update:2024-04-09 21:11:58